HomeProduct Parameters:
Nickname: 5-ALA-P
MF: C5H12NO7P
MW: 229.125041
Fineness: 98%
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| Product | Aminolevulinic acid phosphate |
| Nickname | 5-ALA-P |
| CAS Number | 868074-65-1 |
| Fineness | 98% |
| Molecular Formula | C5H12NO7P |
| Structural Formula |  |
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| Brief Introduction | High Purity: ≥98% by HPLC, optimized for clinical-grade formulations. Dual Formats: Available as sterile lyophilized powder (vials) or topical cream base (pre-formulated for ease of use). Light-Activated Precision: Converts selectively into protoporphyrin IX (PpIX) in target cells, enabling localized PDT treatment with minimal side effects. Global Compliance: Meets FDA 21 CFR, EMA GMP, and ICH Q7 standards. |
Applications
Medical Dermatology
FDA-Approved Use: Treatment of actinic keratosis (pre-cancerous lesions) and non-melanoma skin cancer (e.g., basal cell carcinoma).
Protocol: 20% ALA-P cream applied topically, followed by 635 nm red light exposure (clinically validated).
Aesthetic Dermatology
Acne PDT: Reduces C. acnes bacteria and sebum production (off-label use with blue light).
Anti-Aging: Enhances collagen remodeling via controlled photodamage (under research).
Oncology Research
Investigational use in prostate cancer and glioblastoma (targeted PpIX accumulation in tumor cells).
Quality & Safety
Certifications: Manufactured in ISO 13485-certified facilities; supports Drug Master File (DMF) submissions.
Stability: 24-month shelf life at 2–8°C (lyophilized form); inert gas-packed for oxidation resistance.
Safety Data: Non-mutagenic (AMES test negative), LD50 >2000 mg/kg (oral, rat).
| Package | Solid | 1KG / Foil bag |
| 25KG / Cardboard drum | ||
| Liquid | 200L / Chemical bucket | |
| 1T / Tonne drum | ||
| Transport | Depending on the situation, you can choose either air or sea freight | |
